We work with the best!
We work with a wide range of customers ranging from human, animal and environmental diagnostic companies to universities, research institutes and those operating in the pharmaceutical industry focused on oligonucleotide therapeutics development.
Therapeutics generally refers to the treatment and care of a patient to prevent and overcome disease or alleviate pain or injury. Oligonucleotide technologies continue to demonstrate tremendous potential in developing therapies for various inherited genetic diseases and acquired diseases. Prominent technologies include antisense oligonucleotides (ASO), short interfering siRNAs, long noncoding RNAs (lncRNAs), microRNAs (miRNAs) and antagomiRs, and DNAzymes. We have significant experience in manufacturing these oligonucleotides with various chemistries, and can provide:
Antisense Oligonucleotides (ASO)
microRNAs and antagomiRs/antimiRs
GuideRNAs for CRISPR/Cas9
A wide range of diagnostic kits for both home and laboratory use require high quality probes or primers that target specific markers to allow efficient disease detection or patient sensitivities. We provide high quality oligonucleotides and tailored design capabilities to enable high specificity that suit our customers’ needs. Using our oligonucleotides, customers are able to accelerate their development and validation process, resulting in faster market ready products. Examples of products used in diagnostics include:
How a drug is delivered to a particular area or tissue type is crucial in defining its effectiveness. At SynGenis we provide more than just linkers for attaching a desired delivery cargo. We provide antisense oligonucleotides, siRNAs, micorRNAs, antimiRs and DNAzymes with various cargos including fatty acids (palmitoyl, myristoyl), Vitamins (Vitamin-E), Cholesterol, and N-Acetyl galactosamine (GalNAc). Using these alternative cargos improves the targeted organ delivery. In addition, we also undertake custom conjugation chemistries tailored to our customers’ needs.